The vaccination against the deadly COVID-19 started in the United States on Monday with New York-based nurse Sandra Lindsay becoming the first person in America to receive a dose of the Pfizer-BioNTech.

The death toll in the US has crossed a staggering 300,000.

“It didn’t feel any different from taking any other vaccine,” Lindsay said as quoted by AFP.

Lindsay works as a critical care nurse at the Long Island Jewish Medical Center.

“I hope this marks the beginning of the end of the very painful time in our history,” she added.

The US has reported highest number of coronavirus cases — 16.3 million. President Donald Trump took to Twitter to congratulate the nation and world, saying: “First Vaccine Administered. Congratulations USA! Congratulations WORLD!”

President-elect Joe Biden said in a tweet: “Stay hopeful – brighter days ahead”.

One of the biggest challenge for the country is that the anti-vaccine movement is going strong and it is hard to convince the Americans to take a dose of vaccine.

“My biggest concern is the level of hesitancy in the country. I really hope we are going to be able to change that,” Moncef Slaoui, head of the government’s vaccine rollout program Operation Warp Speed, told CBS.

As many as 35,000 people have died due to the coronavirus alone in the New York state.

“It’s going to take months before the vaccine hits critical mass. So, this is the light at the end of the tunnel, but it’s a long tunnel,” New York state Governor Andrew Cuomo said.

“I believe this is the weapon that will end the war. We have planes, trains and automobiles moving this all over the state right now. We want to get it deployed, and we want to get it deployed quickly,” he added.